The American Chamber of Commerce in Bangladesh (AmCham) was formally established in 1996 having been duly registered with the Joint Stock Companies of Bangladesh to promote the economic relationships between Bangladesh and the United States. Earlier, AmCham used to operate as American Bangladesh Economic Forum (ABEF) since 1988. AmCham holds the full Membership of the Asia Pacific Council of American Chambers of Commerce (APCAC). AmCham Bangladesh has also been accredited as a member of the U.S. Chamber of Commerce.

The membership of the AmCham includes US Companies doing business in Bangladesh, Bangladesh Companies whose primary business is representing US produced goods and services; and non-profit organizations of United States origin.